A Eubacterial Origin for the Human tRNA Nucleotidyltransferase? [PDF]
Biological Chemistry, 2001 tRNA CCA-termini are generated and maintained by tRNA nucleotidyltransferases. Together with poly(A) polymerases and other enzymes they belong to the nucleotidyltransferase superfamily. However, sequence alignments within this family do not allow to distinguish between CCA-adding enzymes and poly(A) polymerases. Furthermore, due to the lack of sequence
Subrata Jana
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The influence of spermidine on the reaction of RNA nucleotidyltransferase
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1968 Abstract 1. 1. RNA synthesis, catalyzed by RNA nucleotidyltransferase ( Escherichia coli B) and directed by native, double-stranded DNA, is significantly increased by spermidine. 2. 2. By use of doubly labeled ATP ([8- 14 C]- and [γ- 32 P]-) and by zone centrifugation, we could show that, in the presence of spermidine, more RNA chains are ...
Eiko E. Petersen, Hans Kröger, U. Hagen
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Terminal nucleotidyltransferase <i>Tent2</i> microRNA A-tailing enzyme regulates excitatory/inhibitory balance in the hippocampus. [PDF]
RNAWardaszka-Pianka P +13 more
europepmc +2 more sources
Transcriptome analysis of the effects of high temperature on zygotic genome activation in porcine embryos [PDF]
Scientific ReportsDamage to the development of porcine gametes and embryos caused by high temperatures (HT) is one of the main reasons for the decline in the economic benefits of the livestock industry.
Ming-Hong Sun +4 more
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THIOL GROUPS IN DEOXYRIBONUCLEIC ACID NUCLEOTIDYLTRANSFERASE [PDF]
Biochemical Journal, 1965 1. The inhibitory effects of iodoacetate, iodoacetamide, p-hydroxymercuribenzoate and sarkomycin were studied in a partially purified preparation of deoxyribonucleic acid nucleotidyltransferase from Landschutz ascites-tumour cells. All of these agents inhibited the activity of the enzyme, and it was shown that the inhibition exerted by the last three ...
HM KEIR, JB SHEPHERD
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cGAS/STING-Independent Induction of Type I Interferon by Inhibitors of the Histone Methylase KDM5B. [PDF]
FASEB JMechanism of HEXIM1 regulation of Type I Interferon. ABSTRACT Studies support the role of hexamethylene bis‐acetamide [HMBA] induced protein 1 (HEXIM1) as a tumor suppressor. We previously reported that the histone demethylase, KDM5B, inhibits the expression of HEXIM1, and KDM5B inhibitors (KDM5Bi) upregulate HEXIM1 expression. As a consequence, KDM5Bi
Montano MM, Yeh IJ, Ketchart W.
europepmc +2 more sources
Recognition of TMV RNA by the tRNA nucleotidyltransferase [PDF]
FEBS Letters, 1974 Claude Bénicourt, Anne‐Lise Haenni
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Heterozygous PNPT1 Variants Cause a Sensory Ataxic Neuropathy. [PDF]
Eur J NeurolABSTRACT Background Biallelic variants in polyribonucleotide‐nucleotidyltransferase‐1 (PNPT1) have been associated with a range of phenotypes from syndromic hearing loss to Leigh's syndrome. More recently, heterozygous variants in PNPT1, have been reported in three families with cerebellar ataxia and prominent sensory neuropathy.
Haddad S +10 more
europepmc +2 more sources
Stimulation and inhibition of deoxyribonucleic acid nucleotidyltransferase by oligodeoxyribonucleotides [PDF]
Biochemical Journal, 1962 HM KEIR
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A Phylogeny of Bacterial RNA Nucleotidyltransferases: Bacillus halodurans Contains Two tRNA Nucleotidyltransferases [PDF]
Journal of Bacteriology, 2005 ABSTRACT We have analyzed the distribution of RNA nucleotidyltransferases from the family that includes poly(A) polymerases (PAP) and tRNA nucleotidyltransferases (TNT) in 43 bacterial species. Genes of several bacterial species encode only one member of the nucleotidyltransferase superfamily (NTSF), and if that protein functions
Patricia Bralley +2 more
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