Results 21 to 30 of about 5,408 (205)

RNA minihelices as model substrates for ATP/CTP:tRNA nucleotidyltransferase [PDF]

Biochemical Journal, 1997
Twenty-one RNA minihelices, resembling the coaxially stacked acceptor- /T-stems and T-loop found along the top of a tRNA's three-dimensional structure, were synthesized and used as substrates for ATP/CTP:tRNA nucleotidyltransferases from Escherichia coli and Saccharomyces cerevisiae.
Zengji LI, Yue Sun, L. David THURLOW
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Identification of residues involved in nucleotidyltransferase activity of JHP933 from helicobacter pyloriby site-directed mutagenesis [PDF]

Archives of Biological Sciences, 2016
Helicobacter pylori is a well-known bacterial pathogen involved in the development of peptic ulcer, gastric adenocarcinoma and other forms of gastric cancer.
Ye Xianren, Zhao Yanhe, Wu Xiuling, Su Yintao, Wu Yunkun, She Feifei   +5 more
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Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola

Frontiers in Microbiology, 2022
A novel chromosome-encoded aminoglycoside O-nucleotidyltransferase AadA33 was identified in Providencia vermicola strain P13. The AadA33 shares the highest amino acid identity of 51.28% with the function characterized AadA31.
Chunlin Feng, Chunlin Feng, Mengdi Gao, Weiyan Jiang, Weina Shi, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Junwan Lu, Junwan Lu, Kewei Li, Hailin Zhang, Yunliang Hu, Qiyu Bao, Qiyu Bao, Qiyu Bao, Xi Lin, Xi Lin   +20 more
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The Terminal Nucleotidyltransferase of Calf Thymus Nuclei

Journal of Biological Chemistry, 1966
Abstract An enzyme from calf thymus nuclei which incorporates ribonucleotides or deoxyribonucleotides into terminal positions of deoxyribonucleic acid has been purified and its mechanism of action elucidated. Distinctions between this enzyme and replicative deoxynucleotidyltransferase (DNA polymerase), the terminal deoxynucleotidyltransferase of calf ...
Michael Gottesman, E.S. Canellakis
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Identification and Characterization of Mammalian Mitochondrial tRNA nucleotidyltransferases [PDF]

Journal of Biological Chemistry, 2001
The CCA-adding enzyme (ATP:tRNA adenylyltransferase or CTP:tRNA cytidylyltransferase (EC )) generates the conserved CCA sequence responsible for the attachment of amino acid at the 3' terminus of tRNA molecules. It was shown that enzymes from various organisms strictly recognize the elbow region of tRNA formed by the conserved D- and T-loops.
Takashi Nagaike, Tsutomu Suzuki, Yukihide Tomari, Chie Takemoto‐Hori, Fumiko Negayama, Kimitsuna Watanabe, Takuya Ueda   +6 more
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Overexpression of FAM46A, a Non-canonical Poly(A) Polymerase, Promotes Hemin-Induced Hemoglobinization in K562 Cells

Frontiers in Cell and Developmental Biology, 2020
FAM46A belongs to the FAM46 subfamily of the nucleotidyltransferase-fold superfamily and is predicted to be a non-canonical poly(A) polymerase. FAM46A has been linked to several human disorders including retinitis pigmentosa, bone abnormality, cancer ...
Hsi-Hsien Lin, Hsi-Hsien Lin, Yu-Ling Lo, Wen-Chih Wang, Kuan-Yeh Huang, Kuan-Yu I, Gin-Wen Chang   +6 more
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ANT(9)-Ic, a Novel Chromosomally Encoded Aminoglycoside Nucleotidyltransferase from Brucella intermedia

Microbiology Spectrum, 2023
Aminoglycoside-modifying enzymes are among the most important mechanisms of resistance to aminoglycoside antibiotics, typically conferring high-level resistance by enzymatic drug inactivation.
Xiusheng Sheng, Wei Lu, Aifang Li, Junwan Lu, Chunhan Song, Jiefeng Xu, Youming Dong, Chunqing Fu, Xi Lin, Mei Zhu, Qiyu Bao, Kewei Li   +11 more
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Identification and Characterization of a Novel Aminoglycoside 3''-Nucleotidyltransferase, ANT(3'')-IId, From Acinetobacter lwoffii

Frontiers in Microbiology, 2021
A novel plasmid-encoded aminoglycoside 3''-nucleotidyltransferase ANT(3")-IId, was discovered in Acinetobacter lwoffi strain H7 isolated from a chick on an animal farm in Wenzhou, China. The whole-genome of A.
Jialei Liang, Jialei Liang, Kexin Zhou, Kexin Zhou, Qiaoling Li, Qiaoling Li, Xu Dong, Xu Dong, Peiyao Zhang, Peiyao Zhang, Hongmao Liu, Hongmao Liu, Hailong Lin, Hailong Lin, Xueya Zhang, Xueya Zhang, Junwan Lu, Junwan Lu, Xi Lin, Xi Lin, Kewei Li, Kewei Li, Teng Xu, Hailin Zhang, Hailin Zhang, Qiyu Bao, Qiyu Bao, Mei Zhu, Yunliang Hu, Yunliang Hu, Ping Ren, Ping Ren   +31 more
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Purification and Characterization of a Mutant tRNA Nucleotidyltransferase [PDF]

European Journal of Biochemistry, 1980
tRNA nucleotidyltransferase has been extensively purified from a mutant strain of Escherichia coli which displays greatly decreased AMP incorporation, but normal CMP incorporation. The defect in AMP incorporation is retained throughout the purification of the mutant protein. The mutant protein behaves identically to the wild‐type protein with regard to
Murray P. Deutscher, Robert G. McGANN
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TYMV RNA As a substrate of the tRNA nucleotidyltransferase [PDF]

FEBS Letters, 1970
It has been recently shown that in the presence of partly purified enzyme preparations from Escherichia coli and ATP. lhe RNA (M.W. = 2 × 106) of Turnip Yellow Mosaic Virus (TYMV) reacts with valine forming an ester bond analogous to that existing in aminoacyltRNA: lhe valine estcrifies the., -terminal adenosine ofTYMV RNA II. 21.
Simon Litvak, François Chapeville, D.S. Carré   +2 more
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