Results 131 to 140 of about 2,090,052 (356)

Performance of Seven Tree Breeding Strategies Under Conditions of Inbreeding Depression

G3: Genes, Genomes, Genetics, 2016
In the domestication and breeding of tree species that suffer from inbreeding depression (ID), the long-term performance of different breeding strategies is poorly known.
Harry X. Wu, Henrik R. Hallingbäck, Leopoldo Sánchez   +2 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The prognostic significance of epoxide hydrolases in colorectal cancer

Biochemistry and Biophysics Reports
Colorectal cancer (CRC) is a common malignant cancer. Epoxide hydrolases (EHs) are involved in the development of cancer by regulating epoxides, but their relationship with CRC is unclear.
Lichao Cao, Ying Ba, Fang Chen, Dandan Li, Shenrui Zhang, Hezi Zhang   +5 more
doaj  

Single-Particle Distributions in Multi-Chain Model with successive collision for High-Energy Nucleus-Nucleus collisions [PDF]

arXiv, 2012
High-energy nucleus-nucleus collisions are studied in multi-chain model with successive collision. Analytic forms for single-particle distribution are derived.
arxiv  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

More on a Curious Nucleus [PDF]

arXiv, 2018
Harold Simmons introduced a pre-nucleus and its associated nucleus that measure the subfitness of a frame in Simmons [2010]. In this paper we continue the study if this pre-nucleus. We answer the questions posed in Simmons [2010].
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Strangeness dynamics in relativistic nucleus-nucleus collision

, 2003
We investigate hadron production as well as transverse hadron spectra in nucleus-nucleus collisions from 2 $A\cdot$GeV to 21.3 $A\cdot$TeV within two independent transport approaches (UrQMD and HSD) that are based on quark, diquark, string and hadronic ...
Adler, Adler, Afanasiev, Ahle, Ahle, Ahmad, Andersson, Antinori, Barannikova, Bass, Bearden, Bjorken, Bleicher, Bratkovskaya, Bratkovskaya, Bratkovskaya, Bravina, Cassing, Cassing, Cassing, Cassing, Cleymans, Danielewicz, E.L Bratkovskaya, Filimonov, Fodor, Friese, Förster, Gaździcki, Gaździcki, Geiss, Geiss, Gorenstein, H Stöcker, H Weber, Hagiwara, Karsch, Karsch, Klay, Kliemant, Kraus, Lee, Lin, M Bleicher, M Reiter, M van Leeuwen, Martemyanov, Mischke, Nikonov, Ouerdane, Pinkenburg, Rafelski, Redlich, S Soff, Sahu, Shuryak, Soff, Soff, Sorge, Stöcker, van Hecke, Van Hove, W Cassing, Weber, Weber   +64 more
core   +1 more source

The manifestation of intonational focus in Castilian Spanish

Catalan Journal of Linguistics, 2003
In this paper we study the phonological manifestation of various intonational focus domains in Castilian Spanish. We propose that downstep is one of the intonational signallers of focus in this language.
Mercedes Cabrera Abreu, María Luisa García Lecumberri   +1 more
doaj   +1 more source