Results 181 to 190 of about 2,194,144 (349)

Opioid induces increased DNA damage in prefrontal cortex and nucleus accumbens

open access: hybrid, 2023
Yunwanbin Wang   +5 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Thalamic Neuromodulation: New Frontiers. [PDF]

open access: yesEpilepsy Curr
Hsu J   +6 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Particle background characterization and prediction for the NUCLEUS reactor CE ν NS experiment. [PDF]

open access: yesEur Phys J C Part Fields
Abele H   +59 more
europepmc   +1 more source

GPSeq reveals the radial organization of chromatin in the cell nucleus

open access: green, 2020
Gabriele Girelli   +10 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Patagomaia could be a gondwanatherian

open access: yesScientific Reports
Hans P. Püschel   +3 more
doaj   +1 more source

Nucleus softens during herpesvirus infection. [PDF]

open access: yesPLoS Pathog
Tervonen A   +15 more
europepmc   +1 more source

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