Results 191 to 200 of about 1,491,280 (348)

From genotype to phenotype: decoding mutations in blasts by holo-tomographic flow cytometry. [PDF]

Light Sci Appl
Pirone D, Di Natale C, Di Summa M, Mosca N, Giugliano G, Schiavo M, Florio D, Marasco D, Maffettone PL, Miccio L, Memmolo P, Ferraro P.   +11 more
europepmc   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Horizontal gaze-evoked nystagmus in pontine gaze palsy: patterns and anatomical correlates. [PDF]

Front Neurol
Choi SY, Choi JH, Kim HS, Lee JY, Lee SU, Lee SH, Kim JM, Kim HA, Park JY, Choi KD.   +9 more
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Hyperuricaemia is associated with smaller volumes in the caudate nucleus head and putamen. [PDF]

Brain Commun
Omori N, Ishida M, Takamura M, Abe S, Nagai A.   +4 more
europepmc   +1 more source

ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS [PDF]

, 1943
Albert Claude, James S. Potter
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Genome-wide identification and characterization of m6A regulatory genes in Soybean: Insights into evolution, miRNA interactions, and stress responses. [PDF]

PLoS One
Sayed SB, Rabbi MA, Debnath JP, Hossen K, Ghosh A.   +4 more
europepmc   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Cell types and neuronal genetic architecture in the rat CSF-contacting nucleus and the role of 5-HT in this nucleus in mediating morphine addiction through the brain-CSF circuit. [PDF]

Front Neurosci
Li Y, Gui B, Zhang Y, Zhang L.
europepmc   +1 more source