Results 221 to 230 of about 1,534,545 (314)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

The pyrogenic mediator prostaglandin E₂ elicits warmth seeking via EP3 receptor-expressing parabrachial neurons: a potential mechanism of chills. [PDF]

J Physiol
Yahiro T, Nakamura Y, Nakamura K.
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Particle background characterization and prediction for the NUCLEUS reactor CE ν NS experiment. [PDF]

Eur Phys J C Part Fields
Abele H, Angloher G, Arnold B, Corona MA, Bento A, Bossio E, Buchsteiner F, Burkhart J, Cappella F, Cappelli M, Casali N, Cerulli R, Cruciani A, Del Castello G, Del Gallo Roccagiovine M, Dorer S, Erhart A, Friedl M, Fichtinger S, Ghete VM, Giammei M, Goupy C, Hauff D, Jeanneau F, Jericha E, Kaznacheeva M, Kluck H, Langenkämper A, Lasserre T, Lhuillier D, Mancuso M, Martin R, Mauri B, Mazzolari A, McCallin L, Neyrial H, Nones C, Oberauer L, Ortmann T, Peters L, Petricca F, Potzel W, Pröbst F, Pucci F, Reindl F, Romagnoni M, Rothe J, Schermer N, Schieck J, Schönert S, Schwertner C, Scola L, Soum-Sidikov G, Stodolsky L, Strauss R, Thalmeier R, Tomei C, Vignati M, Vivier M, Wex A.   +59 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Survodutide acts through circumventricular organs in the brain and activates neuronal regions associated with appetite regulation. [PDF]

Mol Metab
Zimmermann T, Bleymehl K, Haebel P, Perens J, Roostalu U, Hecksher-Sørensen J, Doerr J, Jarosch S, Lam D, Klein H, Pekcec A, Chehimi SN, Crist RC, Reiner BC, Hayes MR, Augustin R.   +15 more
europepmc   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Nucleus softens during herpesvirus infection. [PDF]

PLoS Pathog
Tervonen A, Ruokolainen V, Leclerc S, Tieu K, Lyonnais S, Niskanen H, Chen JH, Gupta A, Kaikkonen MU, Larabell CA, Muriaux D, Mattola S, Conway DE, Ihalainen TO, Aho V, Vihinen-Ranta M.   +15 more
europepmc   +1 more source

Tuning the Electronic Structure and Spin State of Fe─N─C Catalysts Using an Axial Oxygen Ligand and Fe Clusters for High‐Efficiency Rechargeable Zinc–Air Batteries

Advanced Functional Materials, EarlyView.
A FeN4─O/Clu@NC‐0.1Ac catalyst containing atomically‐dispersed FeN4─O sites (medium‐spin Fe2+) and Fe clusters delivered a half‐wave potential of 0.89 V for ORR and an overpotential of 330 mV at 10 mA cm−2 for OER in 0.1 m KOH. When the catalyst was used in a rechargeable Zn–air battery, a power density of 284.5 mW cm−2 was achieved with excellent ...
Yongfang Zhou, Yu Mao, Mengyao Chang, Ziyun Wang, Wenke Xie, Cuizhu Ye, Shanghai Wei, Lars Thomsen, Geoffrey I. N. Waterhouse   +8 more
wiley   +1 more source