Results 201 to 210 of about 17,240 (299)

Quantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 826-838, August 2026.
ABSTRACT Purpose Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...
James A. Bankson   +18 more
wiley   +1 more source

Causal K-Means Clustering. [PDF]

open access: yesJ R Stat Soc Series B Stat Methodol
Kim K, Kim J, Kennedy EH.
europepmc   +1 more source

Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging

open access: yesGenes, Brain and Behavior, Volume 25, Issue 4, August 2026.
C57BL/6J and DBA/2J mice were used to investigate strain and sex‐specific features of the brain connectome in awake animals using magnetic resonance imaging (MRI). By combining resting‐state and diffusion MRI, we found significant differences in the motor, sensory, limbic, and salience networks between C57BL/6J and DBA/2J mice.
Tanzil M. Arefin   +4 more
wiley   +1 more source

Polyphenol oxidase depletion in Nicotiana benthamiana enhances recombinant protein purification and preserves native protein integrity

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1283-1293, August 2026.
Polyphenol oxidases (PPOs) depletion preserves endogenous proteins at their predicted molecular weights and enhances detectable enzymatic activities. (a) Less RbcL crosslinking in ppo mutant of Nicotiana benthamiana. Leaf extracts were incubated for 1 h, separated on protein gels, stained with Coomassie or analyzed by Western blot with the anti‐RbcL ...
Kaijie Zheng   +4 more
wiley   +1 more source

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), shows pronounced clinical heterogeneity poorly explained by pathology burden, representing a gap complicating prognosis. As the brain operates as a complex network for information integration, we hypothesized that connectome architecture mediates the ...
Yating Li   +16 more
wiley   +1 more source

Capturing Aleatoric Uncertainty in Climate Models

open access: yesEnvironmetrics, Volume 37, Issue 5, July 2026.
ABSTRACT Internal climate variability arises from the climate system's inherently chaotic dynamics. Quantifying it is essential for climate science, as it enables risk‐based decision‐making and differentiates between externally forced change and internal fluctuations.
Cornelia Gruber   +4 more
wiley   +1 more source

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