Results 231 to 240 of about 91,138 (340)

A surrogate endpoint-based provisional approval causal roadmap, illustrated by vaccine development. [PDF]

Biostatistics
Gilbert PB, Peng J, Han L, Lange T, Lu Y, Nie L, Shih MC, Waddy SP, Wiley K, Yann M, Zafari Z, Ghosh D, Follmann D, Juraska M, Díaz I.   +14 more
europepmc   +1 more source

Estimating Correlations Between Clinical Trial Outcomes Using Generalised Estimating Equations

Oxford Bulletin of Economics and Statistics, Volume 88, Issue 3, Page 553-567, June 2026.
ABSTRACT Accurately estimating the correlations among clinical trial outcomes is crucial for managing the risk of biopharmaceutical investment portfolios. We propose a novel algorithm for estimating correlations in large clinical trial datasets using a generalised estimating equations (GEE) framework.
Yuehao Dai, Andrew W. Lo, Manish Singh, Qingyang Xu, Ruixun Zhang   +4 more
wiley   +1 more source

Comparing causal inference methods for point exposures with missing confounders: a simulation study. [PDF]

BMC Med Res Methodol
Benz L, Levis AW, Haneuse S.
europepmc   +1 more source

Hypothesis testing in the presence of nuisance parameters

, 1996
Maxwell L. King
openalex   +2 more sources

Fully Modified GLS Estimation for Seemingly Unrelated Cointegrating Polynomial Regressions

Oxford Bulletin of Economics and Statistics, Volume 88, Issue 3, Page 473-483, June 2026.
ABSTRACT A new feasible generalized least squares estimator is proposed. Our estimator incorporates (1) the inverse autocovariance matrix of multidimensional errors, and (2) second‐order bias corrections. The resulting estimator has the intuitive interpretation of applying a weighted least squares objective function to filtered data series.
Yicong Lin, Hanno Reuvers
wiley   +1 more source

Experimental Designs for Preclinical Neuroscience Experiments: Part 2-Blocking and Blocked Designs. [PDF]

eNeuro
Reynolds PS.
europepmc   +1 more source

Geometrical Theory on Estimation of Structural Parameter in the Presence of Infinitely Many Nuisance Parameters

, 1983
Шун-ичи Амари, Masayuki Kumon
openalex   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Editorial: Insights in nanobiotechnology 2024/2025: novel developments, current challenges, and future perspectives. [PDF]

Front Bioeng Biotechnol
Rivera Gil P, Celia C, Ciofani G.
europepmc   +1 more source

Neighborhoods as Nuisance Parameters?

, 1999
openaire   +1 more source