Results 101 to 110 of about 5,474,071 (364)

A survey of nulling pulsars using the Giant Meterwave Radio Telescope

open access: yes, 2012
Several pulsars show sudden cessation of pulsed emission, which is known as pulsar nulling. In this paper, the nulling behaviour of 15 pulsars is presented.
Gajjar, Vishal, Joshi, B. C., Kramer, M.
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Isatin-N-sulfonic acid as new, efficient and reusable catalyst for the synthesis of 2-Amido-alkyl-phenols under solvent-free conditions [PDF]

open access: yesشیمی کاربردی روز, 2017
In this research, a simple and highly efficient method for the synthesis of 2-amidoalkyl phenols using isatin-N-sulfonic acid as a solid acidic catalyst has been reported.
محمدعلی زلفی گل   +4 more
doaj   +1 more source

Axisymmetric electrovacuum spacetimes with a translational Killing vector at null infinity

open access: yes, 1999
By using the Bondi-Sachs-van der Burg formalism we analyze the asymptotic properties at null infinity of axisymmetric electrovacuum spacetimes with a translational Killing vector and, in general, an infinite ``cosmic string'' (represented by a conical ...
A Pravdová   +6 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

A Social Support Intervention to Reduce Intentions to Drop-out from Youth Sport: The GAA Super Games Centre

open access: yesPsychosocial Intervention, 2019
Research has highlighted that drop-out from youth sport has emerged to become a global trend with drop-out rates exceeding 30% in some countries. This study aimed to investigate the effect of a change in perceived support on intentions to drop out from ...
David Lavallee   +3 more
doaj   +1 more source

Students’ Achievement Motivation and factors Determining the Quality of Higher Education [PDF]

open access: yesمطالعات روانشناسی تربیتی, 2019
The purpose of this study was to investigate students’ achievement motivation according to factors determining the quality of higher education. A descriptive and correlation design was used for the research with data collected using questionnaire.
asghar zamani, mahtab pooratashi
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

The flexural behavior of multi-layer high performance self-compacting hybrid fibers concrete slabs [PDF]

open access: yesJournal of Structural and Construction Engineering, 2019
Fiber concretes are a new type of composite material in the manufacturing industry, due to lack of information, identification behavioral characteristics requires laboratory studies.
Amirhosein Sahraei moghadam   +2 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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