Results 51 to 60 of about 2,370,534 (302)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Linear Operator Inequality and Null Controllability with Vanishing Energy for Unbounded Control Systems [PDF]
, 2013 We consider a linear boundary or point control system on a Hilbert space $H$ which is null controllable at some time $T_0 >0$. To every initial state $ y_0 \in H$ we associate the minimal ``energy'' needed to transfer $ y_0 $ to $ 0 $ in a time $ T \ge ...
Zabczyk, J. +8 more
core +1 more source
Role of Fishing Cooperatives in Promoting Entrepreneurship Spirit between Their Members [PDF]
تعاون و کشاورزی, 2018 The main purpose of this research was to determine the impacts of fishing cooperatives on promoting entrepreneurship spirit among their members. The population included 1820 members of the three fishing cooperatives in Bushehr province.
Masoud Samian +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Morphology with a null-interface [PDF]
Proceedings of the 15th conference on Computational linguistics -, 1994 We present an integrated architecture for word-level and sentence-level processing in a unification-based paradigm. The core of the system is a CLP implementation of a unification engine for feature structures supporting relational values. In this framework an HPSG-style grammar is implemented.
Harald Trost, Johannes Matiasek
openaire +3 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Themes of Ahmad Azizi’s Poetry [PDF]
ادبیات پایداری, 2017 Ahmad Azizi can be introduced as a mystic and a revolutionary Shi'ite philosopher. A sort of red and revolutionary Shi'ism expressed in the language of mysticism and Islamic philosophy. Azizi has the passion and happiness of Mowlana and that could be the
Mohammad Reza Najjarian, somaye sharooni
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Strategien zur Null-Fehler-Produktion
, 2015 Die Null-Fehler-Produktion zählt heute zu den vorrangigsten Zielen eines jeden Unternehmens. Sie beeinflusst maßgeblich die Wertschöpfung des Unternehmens und stellt damit eine der wichtigsten Stellgrößen für eine nachhaltige Unternehmensstrategie dar ...
Schloske, Alexander
core +1 more source