Results 81 to 90 of about 5,256,026 (319)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Isatin-N-sulfonic acid as new, efficient and reusable catalyst for the synthesis of 2-Amido-alkyl-phenols under solvent-free conditions [PDF]

open access: yesشیمی کاربردی روز, 2017
In this research, a simple and highly efficient method for the synthesis of 2-amidoalkyl phenols using isatin-N-sulfonic acid as a solid acidic catalyst has been reported.
محمدعلی زلفی گل   +4 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

The flexural behavior of multi-layer high performance self-compacting hybrid fibers concrete slabs [PDF]

open access: yesJournal of Structural and Construction Engineering, 2019
Fiber concretes are a new type of composite material in the manufacturing industry, due to lack of information, identification behavioral characteristics requires laboratory studies.
Amirhosein Sahraei moghadam   +2 more
doaj   +1 more source

On universal null sets [PDF]

open access: yesProceedings of the American Mathematical Society, 1981
If all subsets of cardinality less than 2"o of the real line R are Lebesgue measurable then there exists a permutation p of R with p = p-' such that on the a-field generated by S U p(s) there is no continuous probability measure. 1. Let IS I denote the cardinality of the set S.
E. Grzegorek, C. Ryll-Nardzewski
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Students’ Achievement Motivation and factors Determining the Quality of Higher Education [PDF]

open access: yesمطالعات روانشناسی تربیتی, 2019
The purpose of this study was to investigate students’ achievement motivation according to factors determining the quality of higher education. A descriptive and correlation design was used for the research with data collected using questionnaire.
asghar zamani, mahtab pooratashi
doaj   +1 more source

Null Subjects in Northeast English [PDF]

open access: yes, 2011
This paper presents data and analysis relating to null subjects in spoken colloquial English. While English is not a „pro-drop? language (i.e.
Bailey, Laura R.
core  

On correlation functions of Wilson loops, local and non-local operators

open access: yes, 2011
We discuss and extend recent conjectures relating partial null limits of correlation functions of local gauge invariant operators and the expectation value of null polygonal Wilson loops and local gauge invariant operators. We point out that a particular
A Brandhuber   +34 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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