Results 31 to 40 of about 18,239 (246)

About least-squares type approach to address direct and controllability problems [PDF]

, 2015
- We discuss the approximation of distributed null controls for partial differential equations. The main purpose is to determine an approximation of controls that drives the solution from a prescribed initial state at the initial time to the zero target ...
Münch, Arnaud, Pedregal, Pablo
core   +2 more sources

Null Controllability for Wave Equations with Memory

, 2016
We study the memory-type null controllability property for wave equations involving memory terms. The goal is not only to drive the displacement and the velocity (of the considered wave) to rest at some time-instant but also to require the memory term to
Lu, Qi, Zhang, Xu, Zuazua, Enrique
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Local null controllability of the N-dimensional Navier-Stokes system with N-1 scalar controls in an arbitrary control domain

, 2012
In this paper we deal with the local null controllability of the N-dimensional Navier-Stokes system with internal controls having one vanishing component.
E. Fernández-Cara, E. Fernández-Cara, J.-M. Coron, N. Carreño, O.Yu. Imanuvilov, O.Yu. Imanuvilov, R. Temam, S. Guerrero   +7 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Controllability of a fluid-structure interaction system coupling the Navier–Stokes system and a damped beam equation

Comptes Rendus. Mathématique, 2023
We show the local null-controllability of a fluid-structure interaction system coupling a viscous incompressible fluid with a damped beam located on a part of its boundary.
Buffe, Rémi, Takahashi, Takéo
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Exact null controllability, complete stabilizability and continuous final observability of neutral type systems

International Journal of Applied Mathematics and Computer Science, 2017
For abstract linear systems in Hilbert spaces we revisit the problems of exact controllability and complete stabilizability (stabilizability with an arbitrary decay rate), the latter property being related to exact null controllability.
Rabah Rabah, Sklyar Grigory, Barkhayev Pavel   +2 more
doaj   +1 more source

Boundary controllability of parabolic coupled equations [PDF]

, 2010
This paper is concerned with the boundary controllability of non-scalar linear parabolic systems. More precisely, two coupled one-dimensional parabolic equations are considered.
Fernández Cara, Enrique, González Burgos, Manuel, Teresa de Oteyza, María de la Luz de   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source