Results 51 to 60 of about 18,239 (246)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
On the cost of null-control of an artificial advection-diffusion problem
, 2013 In this paper we study the null-controllability of an artificial advection-diffusion system in dimension $n$. Using a spectral method, we prove that the control cost goes to zero exponentially when the viscosity vanishes and the control time is large ...
Cornilleau, Pierre, Guerrero, Sergio
core +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Boundary Controllability of a Pseudoparabolic Equation
Abstract and Applied Analysis, 2013 We deal with the controllability problem for the pseudoparabolic equation by means of boundary controls. Due to the unusual spectrum of this kind of equations, we prove that the null controllability property is false.
Qiang Tao, Hang Gao, Zheng-an Yao
doaj +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
Some controllability results for the N-Dimensional Navier-Stokes and Boussinesq systems with N-1 scalar controls [PDF]
, 2006 In this paper we deal with some controllability problems for systems of the Navier-Stokes and Boussinesq kind with distributed controls supported in small sets.
Fernández Cara, Enrique +3 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Electronic Journal of Qualitative Theory of Differential Equations, 2012 We consider the semilinear heat equation in a bounded domain of $\mathbb{R}^m$. We prove the null controllability of the system with a finite number of constraints on the normal derivative, when the control acts on a bounded subset of the domain.
Carole Louis-Rose
doaj +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source