Results 51 to 60 of about 8,857,554 (290)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Weighted network motifs as random walk patterns
New Journal of Physics, 2022 Over the last two decades, network theory has shown to be a fruitful paradigm in understanding the organization and functioning of real-world complex systems.
Francesco Picciolo +3 more
doaj +1 more source
Appendix A. Discussion of alternative null models.
, 2016 Discussion of alternative null ...
C. O. Webb (2914652) +2 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice [PDF]
, 2017 Targeted mutant models are common in mechanistic toxicology experiments investigating the absorption, metabolism, distribution, or elimination (ADME) of chemicals from individuals.
Moore, David D. +10 more
core +4 more sources
Lightning network: a second path towards centralisation of the Bitcoin economy
New Journal of Physics, 2020 The Bitcoin lightning network (BLN), a so-called ‘second layer’ payment protocol, was launched in 2018 to scale up the number of transactions between Bitcoin owners.
Jian-Hong Lin +4 more
doaj +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Ecological patterns of blood-feeding by kissing-bugs (Hemiptera: Reduviidae: Triatominae)
Memorias do Instituto Oswaldo Cruz, 2011 Host use by vectors is important in understanding the transmission of zoonotic diseases, which can affect humans, wildlife and domestic animals. Here, a synthesis of host exploitation patterns by kissing-bugs, vectors of Chagas disease, is presented. For
Jorge Eduardo Rabinovich +5 more
doaj +1 more source
Null Subjects in Northeast English [PDF]
, 2011 This paper presents data and analysis relating to null subjects in spoken colloquial English. While English is not a „pro-drop? language (i.e.
Bailey, Laura R.
core
Appendix A. MATLAB code of null models.
, 2016 MATLAB code of null ...
Marcelo A. Aizen (333967) +1 more
core +1 more source