Results 41 to 50 of about 895,352 (296)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Null Subjects in Non-Pro-Drop Languages: The Lens on French

Languages
The contrast between languages such as Italian that allow subjects of tensed sentences to be null (i.e., pro-drop languages) and those like French that do not (i.e., non-pro-drop languages) is a classic issue for comparative syntactic research ...
Mara Frascarelli, Giorgio Carella
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

On the rapid use of verb-control information in sentence processing

Frontiers in Psychology
A central topic in psycholinguistics is the study of how and when the parser assigns an antecedent to referentially-dependent elements. One such referentially-dependent element is the null subject of non-finite clauses.
Josep Demestre
doaj   +1 more source

The role of prosody in overt pronoun resolution in a null subject language and in a non-null subject language: A production study

Glossa, 2019
In this study, we investigate how prosodic cues are used when an overt pronoun is associated with either a subject or an object antecedent in Italian and in Swedish.
Chiara Gargiulo, Mechtild Tronnier, Petra Bernardini   +2 more
doaj   +2 more sources

Teleportation seen from space-time [PDF]

, 2008
Formal similarity between Minkowski tetrads and Bell bases allows to think of metric tensors in terms of quantum teleportation protocols. The role of null tetrads for quantum information processing is different.
Czachor, Marek
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Reconsidering the syntax of interrogatives in Caribbean Spanish. With especial reference to Dominican Spanish

Isogloss, 2020
This paper readdresses one of the most conspicuous syntactic traits of varieties of Caribbean Spanish that has been on the research agenda ever since its detection almost a hundred years ago: the preverbal occurrence of subjects in interrogatives with a ...
Michael Zimmermann
doaj   +3 more sources

Wide-focus subject-verb inversion in Ibero-Romance: A locative account

Glossa, 2016
This paper explores the hypothesis that wide-focus subject-verb inversion in Ibero-Romance is a type of locative inversion, involving a null locative argument.
Alice Corr
doaj   +2 more sources

Simulating children's null subjects [PDF]

Proceedings of the 32nd annual meeting on Association for Computational Linguistics -, 1994
This paper reports work in progress on a sentence generation model which attempts to emulate certain language output patterns of children between the ages of one and one-half and three years. In particular, the model addresses the issue of why missing or phonetically "null" subjects appear as often as they do in the speech of young English-speaking ...
openaire   +1 more source