Results 31 to 40 of about 372,385 (285)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

O parâmetro Pro-drop e a aquisição de segunda língua

open access: yesSemina: Ciências Sociais e Humanas, 2011
Within the Government and Binding theory (GB), it is assumed the man is equipped with some innate language structure, Universal Grammar (UG), which contains a set of inviolable principles plus some open parameters which are set by experience.
Sonia Maria Lazzarini Cyrino
doaj   +1 more source

Holographic approach to thermalization in general anisotropic theories

open access: yesJournal of High Energy Physics, 2021
We employ the holographic approach to study the thermalization in the quenched strongly-coupled field theories with very general anisotropic scalings including Lifshitz and hyperscaling violating fixed points.
Po-Chun Sun, Da-Shin Lee, Chen-Pin Yeh
doaj   +1 more source

Null subjects in european and Brasilian Portuguese [PDF]

open access: yes, 2005
The goals of this paper are twofold: a) to provide a structural account of the effects of the informal ‘Avoid Pronoun Principle’, proposed in Chomsky (1981: 65) for the Null Subject Languages (NSLs), and b) to compare, in European and Brazilian ...
Barbosa, Pilar   +2 more
core  

A tutorial on group effective connectivity analysis, part 2: second level analysis with PEB [PDF]

open access: yes, 2019
This tutorial provides a worked example of using Dynamic Causal Modelling (DCM) and Parametric Empirical Bayes (PEB) to characterise inter-subject variability in neural circuitry (effective connectivity).
Cagnan, Hayriye   +6 more
core   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

To Inflect or Not to Inflect Is the Question Indeed: Infinitives in Second Language (L2) Portuguese

open access: yesJournal of Portuguese Linguistics, 2007
In light of the predictions of two competing approaches to adult L2 acquisition – Full Access (FA) (e.g., White 1989, 2003; Schwartz & Sprouse 1996) and Failed Features (FF) (e.g., Hawkins & Chan 1997; Liceras & Díaz, 1999) – the present ...
Jason Rothman, Michael Iverson
doaj   +2 more sources

Confronting fact and theory in the discovery of Brazilian Portuguese grammar

open access: yesRevista Linguística, 2020
This paper shows interesting questions and results that one can obtain when we combine the variationist methodology with the generative theories in the analysis of data.
Mary Kato
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Information structure, subject positions, and the cartography of the preverbal field in Cibaeño Dominican Spanish

open access: yesIsogloss
Early generative studies on grammatical subjects produced two key findings: the Extended Projection Principle (Chomsky, 1982), and the Null Subject Parameter (NSP, e.g.
Timothy Gupton
doaj   +1 more source

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