Results 71 to 80 of about 44,879 (298)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Causes And Legal Status Of The Absolute Nullity Of The Civil Legal Act [PDF]

Social Sciences and Education Research Review, 2018
The significance of invalidity as a civil law institution is quite clear and concise, namely it is that sanction of civil law that affects the legal act in the case of non- compliance with the legal provisions governing its validity. Therefore, the legal
Adrian NICOLESCU
doaj  

The Legal Effect of a Judgment Declaring the Invalidity of the Dissolution of a Joint-Stock Company on Transactions Concluded Post-Dissolution [PDF]

Faṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī
Joint-stock companies may be dissolved for various reasons, as specified in the 1968 Act Amending a Part of the Commercial Code. The authority for dissolution may rest with the extraordinary general assembly of the company or with a body designated by ...
javad niknejad
doaj   +1 more source

Stability Theory for Nullity and Deficiency of Linear Relations

Abstract and Applied Analysis, 2021
Let A and B be two closed linear relations acting between two Banach spaces X and Y, and let λ be a complex number. We study the stability of the nullity and deficiency of A when it is perturbed by λB. In particular, we show the existence of a constant ρ>
Silas Luliro Kito, Gerald Wanjala
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The nullity of the net Laplacian matrix of a signed graph

The American Journal of Combinatorics
The net Laplacian matrix of a signed graph \(\Gamma = (G, \sigma)\), where \(G = (V(G),E(G))\) is an unsigned graph (referred to as the underlying graph) and \(\sigma: E(G) \rightarrow \{-1, +1\}\) is the sign function, is defined as \(L^{\pm}(\Gamma) =
Zhuang Xiong
doaj   +1 more source

An upper bound of the nullity of a graph in terms of order and maximum degree

Linear Algebra and its Applications, 2018
Let G be a finite undirected graph without loops and multiple edges. By η , Δ and n we respectively denote the nullity, the maximum vertex degree and the order of G. In [10] , it was proved that η ≤ n − 2 ⌈ n − 1 Δ ⌉ when G is a tree.
Qi Zhou, Dein Wong, D. Sun
semanticscholar   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source