Results 51 to 60 of about 5,762 (302)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Index and nullity of proper biharmonic maps in spheres [PDF]
In recent years, the study of the bienergy functional has attracted the attention of a large community of researchers, but there are not many examples where the second variation of this functional has been thoroughly studied.
S. Montaldo, C. Oniciuc, A. Ratto
semanticscholar +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
This comment approaches the most controversial facets of the invalidity action of administrative acts. It is particularly focused on the admission process of the invalidity action, and on the scope of the limits of the review of administrative acts ...
Carmen Agoués Mendizabal
doaj +1 more source
A sharp upper bound of the nullity of a connected graph in terms of order and maximum degree
The nullity η ( G ) of G is the multiplicity of 0 as an eigenvalue of A ( G ) . In this paper, we completely solve the following conjecture proposed by Zhou, Wong and Sun in [Linear Algebra and its Applications, 555 (2018) 314-320]: Let G be a connected ...
Zhiwen Wang, Ji-Ming Guo
semanticscholar +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
On The Nullity of Generalized Rooted T-Tuple With B-Bridge Coalescence Graphs
In this paper, we determine the nullity of generalized rooted t-tuple coalescence graphs and the nullity of generalized rooted t-tuple with b-bridge coalescence graphs. Finally, the nullity of generalized rooted t-tuple with b-path coalescence graph and (
Nechirvan B. Ibrahim
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Reflection on Option for Delayed Payment of the Price [PDF]
Option is one of the most important causes of dissolution of contracts, which has various types in the jurisprudence of Islamic religions and legal systems of the world.
Ali Nosrati
doaj
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source

