Results 51 to 60 of about 40,960 (273)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Reflection on Option for Delayed Payment of the Price [PDF]

open access: yesآموزه‌‌های فقه مدني, 2020
Option is one of the most important causes of dissolution of contracts, which has various types in the jurisprudence of Islamic religions and legal systems of the world.
Ali Nosrati
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

El matrimonio de conveniencia o complacencia como problema jurídico en el fenómeno migratorio

open access: yesRazón Crítica, 2021
El fenómeno migratorio trae aparejados varios problemas de carácter social que indicen de manera directa e indirecta en el derecho, en función del tratamiento que se le dé a estos aspectos por la normativa interna e internacional, se producen situaciones
Ester Mocholi
doaj   +1 more source

The inertia of weighted unicyclic graphs [PDF]

open access: yes, 2013
Let $G_w$ be a weighted graph. The \textit{inertia} of $G_w$ is the triple $In(G_w)=\big(i_+(G_w),i_-(G_w), $ $ i_0(G_w)\big)$, where $i_+(G_w),i_-(G_w),i_0(G_w)$ are the number of the positive, negative and zero eigenvalues of the adjacency matrix $A ...
Feng, Lihua   +2 more
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Causes And Legal Status Of The Absolute Nullity Of The Civil Legal Act [PDF]

open access: yesSocial Sciences and Education Research Review, 2018
The significance of invalidity as a civil law institution is quite clear and concise, namely it is that sanction of civil law that affects the legal act in the case of non- compliance with the legal provisions governing its validity. Therefore, the legal
Adrian NICOLESCU
doaj  

The Legal Effect of a Judgment Declaring the Invalidity of the Dissolution of a Joint-Stock Company on Transactions Concluded Post-Dissolution [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī
Joint-stock companies may be dissolved for various reasons, as specified in the 1968 Act Amending a Part of the Commercial Code. The authority for dissolution may rest with the extraordinary general assembly of the company or with a body designated by ...
javad niknejad
doaj   +1 more source

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