Results 71 to 80 of about 5,762 (302)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The nullity of the net Laplacian matrix of a signed graph

The American Journal of Combinatorics
The net Laplacian matrix of a signed graph \(\Gamma = (G, \sigma)\), where \(G = (V(G),E(G))\) is an unsigned graph (referred to as the underlying graph) and \(\sigma: E(G) \rightarrow \{-1, +1\}\) is the sign function, is defined as \(L^{\pm}(\Gamma) =
Zhuang Xiong
doaj   +1 more source

بطلان الإجراءات في نظام المرافعات الشرعية السعودي لسنة 1435هـ "دراسة تحليلية لنص المادة (5) من نظام المرافعات الشرعية" / Invalidity of Procedures in the Saudi Sharia Procedural Law (1435 AH) "An Analytical Study of Article 5" [PDF]

مجلة البحوث الفقهیة والقانونیة
 تظهر أهمية نظرية البطلان بصفة خاصة في نطاق إجراءات التقاضي (قانون الإجراءات المدنية) الذي يعني بتنظيم كافة إجراءات التقاضي كالجهة المختصة التي يتم التقاضي أمامها وكيفية التقاضي وكيفية تنفيذ الأحكام، ولا سبيل لاحترام تلك القواعد والأوامر إلا عن طريق ...
سامي عبد الحميد إبراهيم أحمد
doaj   +1 more source

Metric f-Contact Manifolds Satisfying the (κ, μ)-Nullity Condition

Mathematics, 2020
We prove that if the f-sectional curvature at any point of a ( 2 n + s ) -dimensional metric f-contact manifold satisfying the ( κ , μ ) nullity condition with n > 1 is independent of the f-section at the point, then it is constant on the manifold ...
A. Carriazo, L. Fernández, E. Loiudice
semanticscholar   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Nullity in the Ordonnance

, 2017
Introduction For the past two centuries, French legal doctrine has tried to elaborate a comprehensive theory of nullity to remedy the absence of such a framework in the Code civil . Due to the variety of sources in the Ancien Regime , the rules regarding nullity formed an intricate whole prior to the enactment of the Code civil .
openaire   +2 more sources

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

An upper bound of the nullity of a graph in terms of order and maximum degree

Linear Algebra and its Applications, 2018
Let G be a finite undirected graph without loops and multiple edges. By η , Δ and n we respectively denote the nullity, the maximum vertex degree and the order of G. In [10] , it was proved that η ≤ n − 2 ⌈ n − 1 Δ ⌉ when G is a tree.
Qi Zhou, Dein Wong, Dongqi Sun
semanticscholar   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source