Results 101 to 110 of about 28,455,638 (326)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Characterization of the Rivlin-Ericksen Viscoelastic Fluid in the Presence of a Magnetic Field and Rotation

open access: yesEngineering Transactions, 2014
A layer of Rivlin-Ericksen viscoelastic fluid heated from below is considered in the presence of an uniform vertical magnetic field and rotation. Following the linearized stability theory and normal mode analysis, this paper mathematically establishes ...
Ajaib S. BANYAL
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Improvement of the finite element method equations conditioning for the magnetic field-circuital problems

open access: yesArchives of Electrical Engineering, 2017
The presented systems with magnetically coupled windings are solved with the finite element method. If the issue of voltage supply is analyzed, a system of linear equations with a partially skew-symmetric sparse matrix is obtained. Iterative methods used
Gołębiowski Marek
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Baryon-number-violating nucleon decays in sterile neutrino effective field theories

open access: yesJournal of High Energy Physics
The search for baryon-number-violating (BNV) nucleon decay provides an in- triguing probe of new physics beyond the Standard Model (SM). Future neutrino experiments will improve the sensitivity to BNV nucleon decays and can serve to search for dark ...
Tong Li   +2 more
doaj   +1 more source

Evaluation of The Water Stress and Irrigation Management Effects on Soil CO2 Emission, Water Productivity and Soybean Yield (Glycine max L.) [PDF]

open access: yesپژوهشهای زراعی ایران
IntroductionThe challenges of climate change and increasing greenhouse gas emissions have led to consequences such as global warming and successive droughts.
S Shiukhy-Soqanloo   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Memory for multiple cache locations and prey quantities in a food-hoarding songbird

open access: yesFrontiers in Psychology, 2012
Most animals can discriminate between pairs of numbers that are each less than four without training. However, North Island robins (Petroica longipes), a food hoarding songbird endemic to New Zealand, can discriminate between quantities of items as high
Nicola eArmstrong   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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