Results 111 to 120 of about 16,000,889 (256)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Sums of Squares in Algebraic Function Fields

open access: yes, 2011
We study sums of squares in algebraic function fields over formally real fields, in particular the arithmetic properties of the field of constants that are necessary or sufficient for a small Pythagoras number of the function field ...
Grimm, David
core   +1 more source

BOUNDED GAPS BETWEEN PRIMES IN NUMBER FIELDS AND FUNCTION FIELDS

open access: yes, 2015
. The Hardy–Littlewood prime k-tuples conjecture has long been thought to be completely unapproachable with current methods. While this sadly remains true, startling breakthroughs of Zhang, Maynard, and Tao have nevertheless made significant progress ...
Lemke Oliver, Robert J.   +9 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

On dihedral algebraic function fields [PDF]

open access: yes, 1993
The purpose of this note is to present some results on the arithmetic of dihedral algebraic function ...
Zúñiga, Wilson
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Some Artin-Schreier type function fields over finite fields with prescribed genus and number of rational places

open access: yes, 2007
We give existence and characterization results for some Artin–Schreier type function fields over finite fields with prescribed genus and number of rational places ...
Özbudak, Ferruh, ÇAKÇAK, Emrah
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Inflation-produced magnetic fields in RnF2 and IF2 models

open access: yes, 2008
We reanalyze the production of seed magnetic fields during inflation in (R/m2)nFμνFμν and IFμνFμν models, where n is a positive integer, R the Ricci scalar, m a mass parameter, and Iηα a power-law function of the conformal time η, with α a positive real ...
Fogli, G. L.   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy