Results 91 to 100 of about 3,259,448 (285)

REMARK ON AVERAGE OF CLASS NUMBERS OF FUNCTION FIELDS [PDF]

Korean Journal of Mathematics, 2013
Summary: Let \(k = \mathbb{F}_q(T)\) be a rational function field over the finite field \(\mathbb{F}_q \), where \(q\) is a power of an odd prime number, and \(\mathbb{A} = \mathbb{F}_q[T]\). Let \(\gamma\) be a generator of \(\mathbb{F}_q^*\). Let \(\mathcal{H}_n\) be the subset of \(\mathbb{A}\) consisting of monic square-free polynomials of degree \(
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

On upper bounds of the complexity of functions over nonprime finite fields in some classes of polarized polynomials

Известия Иркутского государственного университета: Серия "Математика", 2016
Recently, the interest to polynomial representations of functions over finite fields and over finite rings is being increased. Complexity of those representations is widely studied.
A. Kazimirov, S. Reymerov
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Classification of function fields with class number three

Journal of Pure and Applied Algebra, 2015
The aim of this paper is to give a complete classification of congruence function fields \(K/{\mathbb F}_q\) with class number \(h_K=3\). The case \(h_K=1\) was solved by \textit{R. E. MacRae} [J. Algebra 17, 243--261 (1971; Zbl 0212.53302)], \textit{M. L. Madan} and \textit{C. S. Queen} [Acta Arith.
Bilhan, Mehpare, Buyruk, Dilek, Ozbudak, Ferruh   +2 more
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A generalization of arithmetic derivative to p-adic fields and number fields [PDF]

Notes on Number Theory and Discrete Mathematics
The arithmetic derivative is a function from the natural numbers to itself that sends all prime numbers to 1 and satisfies the Leibniz rule. The arithmetic partial derivative with respect to a prime p is the p-th component of the arithmetic derivative ...
Brad Emmons, Xiao Xiao
doaj   +1 more source

Tame Class Field Theory for Global Function Fields

, 2015
We give a function field specific, algebraic proof of the main results of class field theory for abelian extensions of degree coprime to the characteristic.
Florian Hess, Florian Hess, Hal Id Hal, Maike Massierer, Maike Massierer   +4 more
core   +1 more source