Results 81 to 90 of about 3,259,448 (285)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Constructions of Dense Lattices of Full Diversity

Trends in Computational and Applied Mathematics, 2020
A lattice construction using Z-submodules of rings of integers of number fields is presented. The construction yields rotated versions of the laminated lattices A_n for n = 2,3,4,5,6, which are the densest lattices in their respective dimensions.
A. A. Andrade, A. J. Ferrari, J. C. Interlando, R. R. Araujo   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The phase sensitivity of a fully quantum three-mode nonlinear interferometer

New Journal of Physics, 2018
We study a nonlinear interferometer consisting of two consecutive parametric amplifiers, where all three optical fields (pump, signal and idler) are treated quantum mechanically, allowing for pump depletion and other quantum phenomena. The interaction of
Jefferson Flórez, Enno Giese, Davor Curic, Lambert Giner, Robert W Boyd, Jeff S Lundeen   +5 more
doaj   +1 more source

On the Fontaine–Mazur Conjecture for Number Fields and an Analogue for Function Fields

Journal of Number Theory, 2000
The conjecture of Fontaine-Mazur says that if \(k\) is a number field, \(l\) a prime, and \(M\) an unramified \(l\)-adic analytic \(l\)-extension of \(k\), then \(M/k\) is a finite extension. This conjecture is wrong for function fields. But the authors show that, if we start with an equivalent conjecture and restrict to special cases, it is possible ...
openaire   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Dynamics and resonance fluorescence from a superconducting artificial atom doubly driven by quantized and classical fields

Physical Review Research
We report an experimental demonstration of resonance fluorescence in a two-level superconducting artificial atom under two driving fields coupled to a detuned cavity.
Xinhui Ruan, Jia-Heng Wang, Dong He, Pengtao Song, Shengyong Li, Qianchuan Zhao, L. M. Kuang, Jaw-Shen Tsai, Chang-Ling Zou, Jing Zhang, Dongning Zheng, O. V. Astafiev, Yu-xi Liu, Zhihui Peng   +13 more
doaj   +1 more source

A strategy to unveil transient sources of ultra-high-energy cosmic rays

EPJ Web of Conferences, 2013
Transient generation of ultra-high-energy cosmic rays (UHECRs) has been motivated from promising candidates of UHECR sources such as gamma-ray bursts, flares of active galactic nuclei, and newly born neutron stars and magnetars.
Takami Hajime
doaj   +1 more source