Results 141 to 150 of about 11,325,403 (303)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
On Fermat's equation over some quadratic imaginary number fields. [PDF]
Res Number Theory, 2018 Ţurcaş GC.
europepmc +1 more source
, 2017 This paper focuses on number fields and the number rings associated with a particular number field. This topic falls under the study of algebra, and in particular algebraic number theory. The motivation of this paper is to discuss the properties of these
Phillips, Gabriel
core
Least squares estimation of regression coefficients of singular random fields observed on a sphere [PDF]
, 2001 We present some results on the rate of convergence to the normal law of the least square estimates of the regression coefficient of random fields with long range dependence observed on a ...
Anh, Vo +5 more
core
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Number fields and function fields: coalescences, contrasts and emerging applications. [PDF]
Philos Trans A Math Phys Eng Sci, 2015 Keating JP, Rudnick Z, Wooley TD.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Normal Algebraic Number Fields [PDF]
Proceedings of the National Academy of Sciences, 1940 MacLane, Saunders, Schilling, O. F. G.
openaire +4 more sources
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source