Results 201 to 210 of about 7,450,401 (335)
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié+16 more
wiley +1 more source
Non-isomorphic abelian varieties with the same arithmetic. [PDF]
Bell J.
europepmc +1 more source
An application of Prohorov's theorem to probabilistic number theory
Patrick Billingsley
openalex +1 more source
Representation Functions of Sequences in Additive Number Theory [PDF]
Melvyn B. Nathanson
openalex +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker+16 more
wiley +1 more source
Methodological issues in consciousness research: theory comparison, the role of empirical evidence, and a replication crisis. [PDF]
Kirkeby-Hinrup A+3 more
europepmc +1 more source
On the theory of ordinal numbers
openaire +4 more sources
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause+6 more
wiley +1 more source