Results 71 to 80 of about 21,735,665 (352)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Restoration of particle number as a good quantum number in BCS theory
, 2000 As shown in previous work, number projection can be carried out analytically for states defined in a quasi-particle scheme when the states are expressed in a coherent state representation.
Allaart +27 more
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Theorem of the complex exponentials
Ratio Mathematica, 2019 This paper describes a new theorem that relates the lengths of the legs of a right triangle with the ratio of three complex exponentials. The big novelty of the theorem consists in transforming two real measures of legs derived from Euclidean geometry ...
Alberto Daunisi
doaj +1 more source
The distribution of ascents of size d or more in compositions [PDF]
Discrete Mathematics & Theoretical Computer Science, 2009 Combinatorics
Charlotte Brennan, Arnold Knopfmacher
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Quantum algorithms for problems in number theory, algebraic geometry, and group theory
, 2012 Quantum computers can execute algorithms that sometimes dramatically outperform classical computation. Undoubtedly the best-known example of this is Shor's discovery of an efficient quantum algorithm for factoring integers, whereas the same problem ...
Sasaki, Yoshitaka, van Dam, Wim
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Fountains, histograms, and q-identities [PDF]
Discrete Mathematics & Theoretical Computer Science, 2003 We solve the recursion S_n=S_n-1-q^nS_n-p, both, explicitly, and in the limit for n→∞, proving in this way a formula due to Merlini and Sprugnoli. It is also discussed how computer algebra could be applied.
Peter Paule, Helmut Prodinger
doaj +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source