Results 91 to 100 of about 7,997 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Deep Encoding: Where Genetic Algorithms and Numeral Systems Meet [PDF]
, 2022 It has been shown empirically that certain benefits can be gained by modelling genetic algorithm encoding as a numeral system and imple-menting mutation as a form of the numeral system’s arithmetic.
DANIEL WARD-WILLIAMS
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Learning Number Notations – Comparison of a Sign-Value and Place-Value System
Journal of Numerical CognitionAlthough numbers are universal, there are great differences between languages and cultures in terms of how they are represented. Numerical notation can influence number processing.
Hanna Weiers +2 more
doaj +1 more source
Altralang Journal, 2023 The Cardinal Numeration in Casamance Creole: Morphosyntactic Uses and Money Counting System ABSTRACT: Even if more than 50% of its lexicon comes from Portuguese, the Casamance Creole is now an autonomous linguistic system.
Noël Bernard BIAGUI
doaj
The Marañón-Huallaga exchange route
Liames, 2019 In this article we claim that stone classifier-based numeral systems in a number of unrelated North-western South American language families/languages such as Kawapanan, Cholón-Hibito, Munichi, and, tentatively, Quingnam emerged due to calquing or loan ...
Luis Miguel Rojas Berscia, Rita Eloranta
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Adaptive Numeral System (ANS) and its applications in data compression [PDF]
This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University LondonThis research explores innovative methodologies for advancing lossless data compression by developing adaptive numeral systems to calculate and ...
Dadoch, Omaar Ayman
core
, 2023 Convolutional neural network (CNN) based methods have succeeded for handwritten numeral recognition (HNR) applications. However, CNN seems to misclassify similarly shaped numerals (i.e., the silhouette of the numerals that look the same).
Md Abdus Samad Kamal +3 more
core +1 more source