Results 121 to 130 of about 7,997 (304)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Numeration systems as dynamical systems–introduction
, 2006 A numeration system originally implies a digitization of real numbers, but in this paper it rather implies a compactification of real numbers as a result of the digitization. By definition, a numeration system with $G$, where $G$ is a nontrivial closed multiplicative subgroup of ${\mathbb{R}}_+$, is a nontrivial compact metrizable space $Ω$ admitting a
openaire +3 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
A CONJECTURE ON NUMERAL SYSTEMS
, 2008 A numeral system is an infinite sequence of different closed normal λ-terms intended to code the integers in λ-calculus. H. Barendregt has shown that if we can represent, for a numeral system, the functions: Successor, Predecessor, and Zero Test, then ...
Karim Nour +2 more
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Numeral Systems of Five Tibeto-Burman Languages of India
, 2020 Numeral system being an important part and parcel of a language needs to be studied linguistically, exploring through its various aspects. This paper is an attempt to show the similarities and variations in the numeral systems of five Tibeto-Burman (TB ...
Mamta, K. ; https://orcid.org/
core
Diversity in the Numeral Systems of Australian Languages
, 2015 While the numeral systems of Australian languages are small, they are not uniform. In this article we shed light on the extent of variation in small numeral systems by systematically surveying 189 languages from Pama-Nyungan and non-Pama-Nyungan families.
Zentz, Jason, Bowern, Claire
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source