Results 41 to 50 of about 380,680 (312)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Accuracy and Stability of Numerical Algorithms [PDF]
Journal of the American Statistical Association, 2002 Robert L. Strawderman +1 more
+5 more sources
Numerical comparison of pipe-column-separation models [PDF]
, 1994 Results comparing six column-separation numerical models for simulating localized vapor cavities and distributed vaporous cavitation in pipelines are presented.
Bergant, A., Simpson, A.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
On phase change and latent heat models in metal additive manufacturing process simulation
Advanced Modeling and Simulation in Engineering Sciences, 2020 This work proposes an extension of phase change and latent heat models for the simulation of metal powder bed fusion additive manufacturing processes on the macroscale and compares different models with respect to accuracy and numerical efficiency ...
Sebastian D. Proell +2 more
doaj +1 more source
On the accuracy of numerical Fourier transforms
Journal of Computational Physics, 1974 Journal of Computational Physics 16 (1974) 396-400. doi:10.1016/0021-9991(74)90049-7 ; Received by publisher: 1973-12-18 ; Harvest Date: 2016-01-04 12:20:03 ; DOI:10.1016/0021-9991(74)90049-7 ; Page Range: 396 ...
Department of Physics University of Florida Gainesville, Florida 32611, USA ( host institution ) +1 more
openaire +3 more sources
Accuracy of numerical solutions using the eulers equation residuals [PDF]
, 1998 In this paper we derive sorne asymptotic properties on the accuracy of numerical solutions. We sIlow tIlat the approximation error of the policy function is of the same order of magnitude as the size of the Euler equation residuals.
Santos, Manuel S.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
accuracy: Tools for Accurate and Reliable Statistical Computing
Journal of Statistical Software, 2007 Most empirical social scientists are surprised that low-level numerical issues in software can have deleterious effects on the estimation process. Statistical analyses that appear to be perfectly successful can be invalidated by concealed numerical ...
Micah Altman +2 more
doaj