Results 231 to 240 of about 1,090,537 (295)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Numerical analysis on the drilling force of pneumatic impactors under different working conditions and structural parameters. [PDF]

Sci Rep
Li D, Tong L, Huang Z, Xu X, Wang S, Mao J, Zhu H, Deng Y, Chen X.   +8 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

The Effects of Vertebral Body Tethering on the Intervertebral Discs and Facet Joints: A Numerical Analysis. [PDF]

Int J Numer Method Biomed Eng
Nicolini LF, Oliveira RC, Tramontini VH, Ribeiro M, de Mello Roesler CR, Fancello EA.   +5 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Numerical Analysis of Laser Thermal Ablation for Gingival and Peri-Implant Inflammation Using Various Laser Irradiation Angles. [PDF]

Int J Numer Method Biomed Eng
Kim D, Kim H, Kim HS.
europepmc   +1 more source

Competitive Sorption and Carrier-Facilitated Transport of Organic Polymers by Clay Minerals in Limestone Media: Experimental Evidence and Numerical Analysis. [PDF]

Environ Sci Technol
Kwarkye N, Ritschel T, Pihan A, Totsche KU.   +3 more
europepmc   +1 more source

Numerical analysis of bearing capacity of winged helical anchor in clayed soil. [PDF]

Sci Rep
Hao D, Zhang Y, Chen Y, Chen R, Kong G, Wu K, Han Y.   +6 more
europepmc   +1 more source

Numerical Analysis of Mask-Based Phase Reconstruction in Phaseless Spherical Near-Field Antenna Measurements. [PDF]

Sensors (Basel)
Guth AA, Abdulsalaam S, Rauhut H, Heberling D.   +3 more
europepmc   +1 more source

Fuzzy-based numerical analysis of Sisko hybrid nanofluid bioconvective flow over a stretched cylinder for osteoarthritis drug delivery. [PDF]

Sci Rep
Karthik V, Asaigeethan P, VarshaVincy A, Thrisha B, Shyamala M, Periyasamy S.   +5 more
europepmc   +1 more source