Results 91 to 100 of about 2,441,168 (288)
Neuronal basis of numerical cognition in the domestic chick [PDF]
, 2015 Numerical cognition is a “core knowledge” shared among different species and probably relying on mechanisms conserved through evolution [1]. In humans and non-human primates higher-order integrative cortices, such as the prefrontal cortex and the ...
Mayer, Uwe +8 more
core
Spatial-Numerical Associations Enhance the Short-Term Memorization of Digit Locations
Frontiers in Psychology, 2018 Little is known about how spatial-numerical associations (SNAs) affect the way individuals process their environment, especially in terms of learning and memory. In this study, we investigated the potential effects of SNAs in a digit memory task in order
Catherine Thevenot +3 more
doaj +1 more source
The emergence of “groupitizing” in children’s numerical cognition
Journal of Experimental Child Psychology, 2014 Improvements in enumeration abilities that emerge over late childhood are primarily thought to reflect perceptual developments such as increases in subitizing limits for small sets and faster shifting of attention associated with serially counting larger sets.
Starkey, Gillian S. +1 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
How Can We Understand Numerical Cognition via Sensorimotor System: The Specific Role of Pointing [PDF]
openNumerous studies show that sensorimotor interactions with the environment facilitate the acquisition of numerical abilities. The present study investigated how grasping and pointing actions impact performance on subsequent numerical tasks, focusing ...
KARADENIZ, CEMRE
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Constructing a Concept of Number
Journal of Numerical Cognition, 2018 Numbers are concepts whose content, structure, and organization are influenced by the material forms used to represent and manipulate them. Indeed, as argued here, it is the inclusion of multiple forms (distributed objects, fingers, single- and two ...
Karenleigh A. Overmann
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source