Results 101 to 110 of about 177,801 (285)

Coordinating visualizations of polysemous action: Values added for grounding proportion [PDF]

, 2013
We contribute to research on visualization as an epistemic learning tool by inquiring into the didactical potential of having students visualize one phenomenon in accord with two different partial meanings of the same concept.
Abrahamson, D, Gutiérrez, JF, Lee, RG, Negrete, AG   +3 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Decision by sampling [PDF]

, 2006
We present a theory of decision by sampling (DbS) in which, in contrast with traditional models, there are no underlying psychoeconomic scales. Instead, we assume that an attribute’s subjective value is constructed from a series of binary, ordinal ...
Abdellaoui, Alba, Allais, Anderson, Anderson, Anderson, Bak, Benartzi, Bentham, Benzion, Bettman, Beyth-Marom, Birnbaum, Bleichrodt, Bordley, Brun, Budescu, Budescu, Budescu, Busemeyer, Camerer, Chapman, Chater, Clarke, Diederich, Dougherty, Dougherty, Dougherty, Erev, Friedman, Garner, Gigerenzer, Gonzalez, González-Vallejo, Gordon D.A. Brown, Green, Gutenberg, Hertwig, Hinson, Hintzman, Hintzman, Ijiri, Johnstone, Juslin, Kahneman, Kahneman, Karelitz, Kirby, Kirby, Laming, Laming, Landauer, Loewenstein, Loewenstein, Loomes, Lund, Mandelbrot, Mazur, Miller, Myerson, Neil Stewart, Nick Chater, Niedrich, Oaksford, Oaksford, Olson, Parducci, Parducci, Payne, Pollmann, Pollmann, Prelec, Prelec, Quiggin, Quiggin, Rachlin, Reagan, Roe, Samuelson, Savage, Schwarz, Shefrin, Shepard, Shiffrin, Simpson, Slovic, Stewart, Stewart, Thaler, Tversky, Tversky, Tversky, Wallsten, Walsh, Weber, Windschitl, Wu, Wu, Zipf   +98 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The Small Number System [PDF]

, 2019
I argue that the human mind includes an innate domain-specific system for representing precise small numerical quantities. This theory contrasts with object-tracking theories and with domain-general theories that only make use of mental models.
Margolis, Eric
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Mathematical difficulties as decoupling of expectation and developmental trajectories [PDF]

, 2014
Recent years have seen an increase in research articles and reviews exploring mathematical difficulties (MD). Many of these articles have set out to explain the etiology of the problems, the possibility of different subtypes, and potential brain regions ...
McLean, Janet F., Rusconi, Elena
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source