Results 71 to 80 of about 4,848,201 (287)

Analysis of the Positional Forward Solution of 2(3-RPS) Parallel-serial Robot Motion Mechanism

open access: yesJixie chuandong, 2018
The parallel-serial robot motion mechanism,compared to the single parallel mechanism,the working space can be largely increased and so as its deflexion capacity,there for,its application foreground is broad.
李峰, 李伟, 梁辉
doaj  

Achieving a Sustainable Environment using Numerical Method for the Solution of Advection Equation in Fluid Dynamics

open access: yesChemical Engineering Transactions, 2018
The paper compares some explicit numerical methods for solving the advection equation that could be used to describe transportation of a pollutant in one direction.
Olusegun Adeyemi Olaiju   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

D-adaptive model for the elasticity problem

open access: yesComputer Assisted Methods in Engineering and Science, 2023
The paper presents some aspects of the formulation and numerical implementation of combined mathematical model "elastic body - Timoshenko plate". The variational problem is formulated. The existence of solution of combined model is considered.
Yarema H. Savula, I van I. Dyyak
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Numerical solution for space and time fractional order Burger type equation

open access: yesAlexandria Engineering Journal, 2018
In this paper, we study the fractional differential operators thereby considering the space and time order Burger type equation with initial condition. The extended finite difference method which is based on shifted Grünwald, Caputo and Riemann formulas ...
Asıf Yokus
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Numerical simulation of drying of Pinus pseudostrobus wood with Comsol Multiphysics [PDF]

open access: yes, 2011
In this work, we present the second part of our investigation. In the first part, we have published a semi-empirical model for drying. In this second part, we present the numerical solution of a drying model for Pinus pseudostrobus (Mexican softwood ...
HERNANDEZ-BAUTISTA, Emilio   +11 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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