Results 91 to 100 of about 1,380,838 (279)
Simplified composite micromechanics for predicting microstresses [PDF]
A unified set of composite micromechanics equations is summarized and described. This unified set is for predicting the ply microstresses when the ply stresses are known.
Chamis, C. C.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
An efficient numerical approach to solve the space fractional FitzHugh–Nagumo model
Advances in Difference Equations, 2019 In this work, we study the numerical approximation for the space fractional FitzHugh–Nagumo model. The numerical scheme is based on the Crank–Nicolson (C–N) method in time and Legendre-spectral method in space.
Jun Zhang +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Examples and CounterexamplesPorous materials can be described either by Biot’s consolidation theory or the Theory of Porous Media (TPM). Depending on the loading regime, permeability or compressibility of the solid matrix, either small or finite deformations occur.
Maximilian Brodbeck +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Another explicit forms of dynamic substructuring approaches using dynamic constraints at joint nodes
Journal of Asian Architecture and Building EngineeringThe dynamic substructuring design describes the dynamic responses in the modal, frequency and physical domains using coupling methods at joint nodes. This paper presents dynamic structuring methods to modify existing substructuring methods by merging the
Minsur Son +3 more
doaj +1 more source