Results 121 to 130 of about 243,906 (306)

Source code and Numerical Examples for Decomposed Quasiconvex Optimization with Application to Generalized Cone Problems [PDF]

open access: yes
This dataset contains source code and numerical examples for quasiconvex sum-of-squares problems via decomposed optimization.Usage Notes The files in the examples folder correspond to the numerical examples provided in Section 6 of the accompanying ...
Cunis, Torbjørn
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Some numerical verification examples for plane stress elasto-viscoplasticity [PDF]

open access: yes, 2019
This paper presents analytical, semi-analytical and numerical reference examples which can be employed for code verification of elasto-viscoplastic models under plane stress conditions.
Dos Santos, Tiago   +3 more
core   +2 more sources

Numerical Analysis of a Fractional Cauchy Problem for the Laplace Equation in an Annular Circular Region [PDF]

open access: yes
The Cauchy problem for the Laplace equation in an annular bounded region consists of finding a harmonic function from the Dirichlet and Neumann data known on the exterior boundary.
Eduardo Hernández Montero   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Stability and Conditioning in Numerical Analysis [PDF]

open access: yes, 2006
The terms stability and conditioning are used with a variety of meanings in Numerical Analysis. All of them have in common the general concept of the response of a computational algorithm to perturbations arising either from the data or from the specific
MAZZIA, Francesca   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Mathematical analysis and numerical methods for pricing pension plans allowing early retirement [PDF]

open access: yes
In this paper, we address the mathematical analysis and numerical solution of a model for pricing a defined benefit pension plan. More precisely, the benefits received by the member of the plan depend on the average salary and early retirement is allowed.
Pascucci, Andrea   +2 more
core   +1 more source

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