Results 221 to 230 of about 12,414 (350)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Deterministic, stochastic, and mean-field PDE models in neuroscience. [PDF]

Front Comput Neurosci
Çetin C, Piqueira JRC, İzgi B, Peker-Dobie A, Ahmetolan S, Özkaya M.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A study of the use of lattice augmentation sequences in the design of an automatic routine for low-dimensional numerical integration

, 2005
Tiancheng Li
openalex   +1 more source

Integrating virtual reality and large language models for team-based non-technical skills training and evaluation in the operating room. [PDF]

NPJ Digit Surg
Barker J, Demirel D, Jackson C, Johansson A, Miraglia R, Hoagland D, Jones SB, Mitchell J, Jones DB, De S.   +9 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Spherical Designs, Discrepancy and Numerical Integration [PDF]

, 1993
Peter J. Grabner, Robert F. Tichy
openalex   +1 more source

SparseTrack: A Physics-Informed Transformer Framework for Real-Time Human Motion Reconstruction from Sparse IMUs. [PDF]

Sensors (Basel)
Balasubramanyam A, Velpanur SM, Jeevarathnam SE, Jayachandra TC, Honnavalli P, Srinivasa G.   +5 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The effect of numerical integration in the finite element method for nonmonotone nonlinear elliptic problems with application to numerical homogenization methods

, 2011
Assyr Abdulle, Gilles Vilmart
openalex   +2 more sources