Results 61 to 70 of about 279,536 (273)

On the Enhancement of the Reconstruction Accuracy obtained with a Multi-Source/Multi-Illumination Inverse Scattering Technique [PDF]

, 2005
This paper explores the possibility of enhancing the available information content of scattered data by means of an innovative Multi-Source strategy.
Franceschini, Davide, Massa, Andrea
core   +4 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Anomalous magneto-oscillations in two-dimensional systems

, 1999
The frequencies of Shubnikov-de Haas oscillations have long been used to measure the unequal population of spin-split two-dimensional subbands in inversion asymmetric systems.
B. Jusserand, C. Kittel, D. Shoenberg, E. A. de Andrada e Silva, E. P. De Poortere, H. L. Störmer, H. Mayer, H.-R. Trebin, J. Bolte, J. Luo, J. Nitta, J. P. Eisenstein, J. P. Lu, L. Onsager, M. Shayegan, M. V. Berry, P. D. Dresselhaus, R. G. Littlejohn, R. Winkler, R. Winkler, R. Winkler, R. Winkler, R. Wollrab, S. J. Papadakis, S. J. Papadakis, T. Ando, U. Ekenberg, U. Rössler, Y. A. Bychkov   +28 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Computational Approach for Differential Equations with Local and Nonlocal Fractional-Order Differential Operators

Journal of Mathematics, 2023
Laplace transform has been used for solving differential equations of fractional order either PDEs or ODEs. However, using the Laplace transform sometimes leads to solutions in Laplace space that are not readily invertible to the real domain by ...
null Kamran, Ujala Gul, Fahad M. Alotaibi, Kamal Shah, Thabet Abdeljawad   +4 more
doaj   +1 more source

Numerical Implementation of the QuEST Function

, 2016
This paper deals with certain estimation problems involving the covariance matrix in large dimensions. Due to the breakdown of finite-dimensional asymptotic theory when the dimension is not negligible with respect to the sample size, it is necessary to ...
Anlauff, Bachega, Bai, Bai, Bai, Bai, Bell, Chen, Chen, Dobriban, El Karoui, Elsheikh, Engle, Guo, Hafner, Haufe, Huang, Ito, Jones, Kumaraswamy, Lam, Ledoit, Ledoit, Ledoit, Ledoit, Ledoit, Ledoit, Li, Markon, Marčenko, Mestre, Michael Wolf, Michaelides, Olivier Ledoit, Pirkl, Pyeon, Rao, Ribes, Schäfer, Silverstein, Silverstein, Silverstein, Stein, Stieltjes, Welsing, Yao, Yao, Zhang   +47 more
core   +1 more source

Numerical inverse transformation for map projections

Computers & Geosciences, 2003
In cartography map projections are used to transform geographical coordinates to plane coordinates. This is called forward transformation. For many geographic information system (GIS) applications paper maps are digitised, and so captured data are integrated into another data set.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Study of noise effects in electrical impedance tomography with resistor networks

, 2011
We present a study of the numerical solution of the two dimensional electrical impedance tomography problem, with noisy measurements of the Dirichlet to Neumann map. The inversion uses parametrizations of the conductivity on optimal grids.
Borcea, Liliana, Mamonov, Alexander V., Vasquez, Fernando Guevara   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source