Results 121 to 130 of about 975,461 (312)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Numerical continuation in nonlinear dynamics with the asymptotic numerical method

open access: yes
This chapter is dedicated to a particular family of methods for numerical continuation, called the asymptotic numerical method(s) (ANM). As it will be shown, it is based on expanding the solution path into a succession of branches in the form of Taylor ...
COCHELIN, Bruno, THOMAS, Olivier
core  

Numerical quadrature methods for singular and nearly singular integrals

open access: yes, 2001
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis is concerned with the development, design, and analysis of simple and efficient numerical quadrature methods for integrals on finite intervals ...
Chunrungsikul, S.   +1 more
core  

A class of Petrov-Galerkin finite element methods for the numerical solution of the stationary convection-diffusion equation. [PDF]

open access: yes, 1996
A class of Petrov-Galerkin finite element methods is proposed for the numerical solution of the n dimensional stationary convection-diffusion equation.
Perella, A.J., Perella, Andrew James
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Application of the Front-Fixing Method to Numerical Modeling of Field Diffusion in Nonlinear Systems

open access: yes, 2009
Application of a finite volume front-fixing method to a thermistor problem with strongly nonlinear material properties is discussed. Advantages and implementation problems of the method are highlighted.
Golosnoy, I.O., Sykulski, J.K.
core  

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