Recent trends in highly accurate and structure-preserving numerical methods for partial differential equations [PDF]
Quan Z. Sheng +3 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The present document presents a review on the use of the finite element software package CODE_BRIGHT to simulate reinforced soil structures (RSS).
Aníbal Moncada +4 more
doaj +1 more source
Multi-Layer Fabric Composites Combined with Non-Newtonian Shear Thickening in Ballistic Protection-Hybrid Numerical Methods and Ballistic Tests. [PDF]
Roszak M +5 more
europepmc +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Should XR Applications Supplement or Replace History Excursions in Education?
Cultural heritages are important out-of-school learning sites in history lessons, but excursions are associated with high organizational effort for teachers. This article explores whether XR applications can replace or supplement school excursions.
Pascal Mosler +4 more
doaj +1 more source
Numerical methods for the detection of phase defect structures in excitable media. [PDF]
Kabus D +4 more
europepmc +1 more source
Numerical Analysis of Flow Field and Heat Transfer of 2D Wavy Ducts and Optimization by Entropy Generation Minimization Method [PDF]
O. Nourani Zonouz, Mehdi Salmanpour
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis. [PDF]
AlShurbaji M +4 more
europepmc +1 more source

