Results 121 to 130 of about 2,801,056 (271)

Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis. [PDF]

Int J Environ Res Public Health, 2023
AlShurbaji M, Kader LA, Hannan H, Mortula M, Husseini GA.   +4 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A Validated Thermal Computational Fluid Dynamics Model of Wine Warming in a Glass

Applied Sciences
Oenophiles are aware that the temperature at the time of drinking can profoundly shape wine’s sensory attributes. Wine is usually served and drunk below room temperature but warms up after pouring due to heat exchange with warmer surroundings. This study
Maximilian Kannapinn, Felix Köhler, Michael Schäfer   +2 more
doaj   +1 more source

Treatise on Analytic Nonlinear Optimal Guidance and Control Amplification of Strictly Analytic (Non-Numerical) Methods. [PDF]

Front Robot AI, 2022
Sands T.
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Deep Learning for Detecting Abandoned Dogs

International Journal of Interactive Multimedia and Artificial Intelligence
This research paper presents a methodology consisting of an algorithm and a workflow for finding abandoned dogs in natural surroundings. We propose a temporal-contextual methodology for identifying abandoned pets in public areas. This involves employing
Oluwakemi Akinwehinmi, Alberto Tena, Francisco Javier Mora, Francesc Solsona, Pedro Arnau del Amo   +4 more
doaj   +1 more source

Numerical Methods in Studies of Liquid Crystal Elastomers. [PDF]

Polymers (Basel), 2021
Soltani M, Raahemifar K, Nokhosteen A, Kashkooli FM, Zoudani EL.   +4 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Accuracy Evaluation of Thermoelastic Stress Analysis with the Use of Experimental and Numerical Methods. [PDF]

Materials (Basel), 2022
Misiewicz R, Moczko P, Bajcar A.
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source