Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Should XR Applications Supplement or Replace History Excursions in Education?
International Journal of Serious GamesCultural heritages are important out-of-school learning sites in history lessons, but excursions are associated with high organizational effort for teachers. This article explores whether XR applications can replace or supplement school excursions.
Pascal Mosler +4 more
doaj +1 more source
Comprehensive Study of a Diabetes Mellitus Mathematical Model Using Numerical Methods with Stability and Parametric Analysis. [PDF]
Int J Environ Res Public Health, 2023 AlShurbaji M +4 more
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Numerical Methods in Studies of Liquid Crystal Elastomers. [PDF]
Polymers (Basel), 2021 Soltani M +4 more
europepmc +1 more source
Numerical Methods for Conservation Laws: From Analysis to Algorithms
, 2017 J. Hesthaven
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Validated Thermal Computational Fluid Dynamics Model of Wine Warming in a Glass
Applied SciencesOenophiles are aware that the temperature at the time of drinking can profoundly shape wine’s sensory attributes. Wine is usually served and drunk below room temperature but warms up after pouring due to heat exchange with warmer surroundings. This study
Maximilian Kannapinn +2 more
doaj +1 more source
Treatise on Analytic Nonlinear Optimal Guidance and Control Amplification of Strictly Analytic (Non-Numerical) Methods. [PDF]
Front Robot AI, 2022 Sands T.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source