Accuracy Evaluation of Thermoelastic Stress Analysis with the Use of Experimental and Numerical Methods. [PDF]
Misiewicz R, Moczko P, Bajcar A.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Constructing Physics-Informed Neural Networks with Architecture Based on Analytical Modification of Numerical Methods by Solving the Problem of Modelling Processes in a Chemical Reactor. [PDF]
Tarkhov D, Lazovskaya T, Malykhina G.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Influence of postural changes on haemodynamics in internal carotid artery bifurcation aneurysm using numerical methods. [PDF]
Ballambat RP +7 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Breakdown of a Nonlinear Stochastic Nipah Virus Epidemic Models through Efficient Numerical Methods. [PDF]
Raza A +3 more
europepmc +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A class of Petrov-Galerkin finite element methods for the numerical solution of the stationary convection-diffusion equation. [PDF]
A class of Petrov-Galerkin finite element methods is proposed for the numerical solution of the n dimensional stationary convection-diffusion equation.
Perella, A.J., Perella, Andrew James
core
Cerebrospinal fluid dynamics coupled to the global circulation in holistic setting: Mathematical models, numerical methods and applications. [PDF]
Toro EF +6 more
europepmc +1 more source

