Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Sensitivity Assessment of Macroscopic Mechanical Responses of Cemented Sand and Gravel to Mesoscopic Parameters Using an Improved MULTIMOORA Method. [PDF]
Shi Z, Li F, Zhang Y.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Iterative spectral methods for Hamilton-Jacobi-Bellman quasi-variational inequality in finance. [PDF]
Lei M, Lu Z.
europepmc +1 more source
Evaluation of replication success: A statistical perspective and extended analysis of the SCORE data. [PDF]
van Aert RCM +2 more
europepmc +1 more source
Using large models and time series forecasting for market reaction analysis. [PDF]
He H, Li X.
europepmc +1 more source
Minimization of Welding Distortion in Large-Scale Welded Structures Using the MAG Method: Numerical and Physical Simulation of the Welding Process. [PDF]
Mróz M, Czech R, Pikuła J, Spólnik M.
europepmc +1 more source
Finite-time and predefined-time dynamical systems for solving strongly pseudomonotone mixed equilibrium problems. [PDF]
Wen Q, Khan VK, Cai QB, Ahmad MK.
europepmc +1 more source
Computational analysis of heat transfer in Darcy Forchheimer magneto hydrodynamic Casson ternary hybrid nanofluid flow through convergent/divergent channel. [PDF]
Lai W, Haq MU, Li J, Khan ZA, Ullah S.
europepmc +1 more source

