YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Numerical model of aluminothermic reduction vessel preheating and charge heating with graphite heating rods. [PDF]
Semenov S, Namy P, Kale A, Tsebe S.
europepmc +1 more source
A Numerical Model for Understanding the Development of Adhesion during Drying of Cellulose Model Surfaces. [PDF]
Kaplan M, Östlund S.
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Noise Levels Due to Commercial and Leisure Activities in Urban Areas: Experimental Validation of a Numerical Model Fed with Crowd Density Estimation Using Computer Vision. [PDF]
Ramón-Turner Ó +12 more
europepmc +1 more source
Idealized hydrodynamical numerical model dataset with no-river runoff at the western tropical North Atlantic. [PDF]
Varona HL, Araujo J, Araujo M, Silva M.
europepmc +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Investigation of inert gas washout methods in a new numerical model based on an electrical analogy. [PDF]
Schmidt C +4 more
europepmc +1 more source
Probabilistic prediction of rock avalanche runout using a numerical model. [PDF]
Aaron J +4 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source

