Results 171 to 180 of about 175,188 (311)

An integrated numerical modelling framework for simulation of the multiphysics in sonoprocessing of materials. [PDF]

Ultrason Sonochem
Qin L, Xiang K, Li L, Tzanakis I, Eskin D, Mi J.   +5 more
europepmc   +1 more source

Experimental Research and Numerical Modelling of the Cold Forming Process of the Inconel 625 Alloy Sheets Using Flexible Punch. [PDF]

Materials (Basel), 2023
Balcerzak M, Żaba K, Hojny M, Puchlerska S, Kuczek Ł, Trzepieciński T, Novák V.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Reconstructing subsurface fracture geometries in rock slope instabilities through ambient vibration-based numerical modelling inversion. [PDF]

Sci Rep
Grechi G, Moore JR, D'Amico S, Martino S.   +3 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Nonlinear Behaviour of Aluminium and Passive Brackets in Ventilated Facades: Experimental Tests and Numerical Modelling. [PDF]

Materials (Basel)
Zawiślak Ł, Schabowicz K, Kopyłow O.
europepmc   +1 more source

A Numerical Modelling Framework for Investigating the Ballistic Performance of Bio-Inspired Body Armours. [PDF]

Biomimetics (Basel), 2023
Ghazlan A, Ngo T, Tan P, Tran P, Xie YM.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Integration of InSAR and numerical modelling to assess tailings pond slope deformation affected by reservoir water. [PDF]

Sci Rep
Lu L, Li M, Chao L.
europepmc   +1 more source

The Significance of Cross-Sectional Shape Accuracy and Non-Linear Elasticity on the Numerical Modelling of Cerebral Veins under Tensile Loading. [PDF]

Biology (Basel), 2023
Fernandes FAO, Silveira CIC.
europepmc   +1 more source