Results 201 to 210 of about 68,332 (263)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
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Numerical modeling for plasmonics
International Journal of Applied Electromagnetics and Mechanics, 2011This contribution is a review paper, concerning mainly the research work made by the authors, about the numerical modeling, in the frequency domain, of both surface and bulk plasmon oscillations induced in metallic nanoparticles with arbitrary shapes by an external electromagnetic field.
G. Miano +2 more
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NUMERICAL MODELLING OF DISCONTINUA
Engineering Computations, 1992Discrete element methods are numerical procedures for simulating the complete behaviour of systems of discrete, interacting bodies. Three important aspects of discrete element programs are examined: (1) the representation of contacts; (2) the representation of solid material; and (3) the scheme used to detect and revise the set of contacts.
PETER A. CUNDALL, ROGER D. HART
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Numerical Modeling of Mudflows
Journal of Hydraulic Engineering, 1997To predict mudflow dynamics a numerical model based on shallow-water equations is developed. Previous work has shown that mudflow behavior can be well represented by a Herschel-Bulkley model. In a laminar regime, generally observed in practice, a wall friction force expression has been theoretically deduced for steady uniform flows.
Laigle, D., Coussot, Philippe
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Acta Mathematica Scientia, 1994
An approach to approximate data by smooth numerical models is described. The idea seems to be ``\dots to fit a smooth numerical model to the data, instead of fitting a curve.'' Theoretical backgrounds are partially available and illustrative examples are discussed.
Xie, Litong, Liu, Jiazhuang
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An approach to approximate data by smooth numerical models is described. The idea seems to be ``\dots to fit a smooth numerical model to the data, instead of fitting a curve.'' Theoretical backgrounds are partially available and illustrative examples are discussed.
Xie, Litong, Liu, Jiazhuang
openaire +2 more sources
Journal of Optical and Fiber Communications Reports, 2004
A procedure for evaluating system performance considering all orders of polarization mode dispersion (PMD) is presented. The method provides engineering rules for computing system penalty introduced by PMD. Computer simulation of PMD induced penalty indicates that for generating a realistic system budget, effect of higher order PMD in presence of ...
D. Chowdhury, M. Mlejnek, Y. Mauro
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A procedure for evaluating system performance considering all orders of polarization mode dispersion (PMD) is presented. The method provides engineering rules for computing system penalty introduced by PMD. Computer simulation of PMD induced penalty indicates that for generating a realistic system budget, effect of higher order PMD in presence of ...
D. Chowdhury, M. Mlejnek, Y. Mauro
openaire +1 more source
2018
This chapter deals with the problem of modelling the behaviour of massive concrete structures. In the last decades, the developments in the field of computational mechanics were significant, so nowadays several numerical techniques are available to this goal, depending on the scale level considered but also on which phenomena/processes are taken into ...
Pesavento F. +4 more
openaire +2 more sources
This chapter deals with the problem of modelling the behaviour of massive concrete structures. In the last decades, the developments in the field of computational mechanics were significant, so nowadays several numerical techniques are available to this goal, depending on the scale level considered but also on which phenomena/processes are taken into ...
Pesavento F. +4 more
openaire +2 more sources