Results 121 to 130 of about 8,966,705 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A numerical study of laterally strained wall-bounded turbulence

, 2009
Direct numerical simulation (DNS) is used to study the effects of mean lateral divergence and convergence on wall-bounded turbulence, by applying uniform irrotational temporal deformations to a plane-channel domain.
Coleman, G.N., Spalart, P.R., Kim, J., Fedorov, D.   +3 more
core   +1 more source

2D and 3D numerical models to evaluate trabecular bone damage. [PDF]

Med Biol Eng Comput, 2021
Buccino F, Colombo C, Duarte DHL, Rinaudo L, Ulivieri FM, Vergani LM.   +5 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Numerical Models of the Connection of Thin-Walled Z-Profile Roof Purlins. [PDF]

Materials (Basel), 2021
Pařenica P, Lehner P, Brožovský J, Krejsa M.   +3 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The short-run dynamics of optimal growth models with delays [PDF]

Differential equations with advanced and delayed time arguments may arise in the optimality conditions of simple growth models with delays. Models with investment gestation lags (time-to-build), consumption gestation lags (habit formation) or learning by
Omar Licandro, Fabrice Collard, Luis A. Puch   +2 more
core  

System Reliability Analysis of Concrete Arch Dams Considering Foundation Rock Wedges Movement: A Discussion on the Limit Equilibrium Method

Infrastructures
In this paper, a discussion on the applicability and limitations of the limit equilibrium method is presented. In this manner, the reliability of a concrete arch dam-foundation system under static loading is evaluated by considering a set of potentially ...
Narjes Soltani, Ignacio Escuder-Bueno, Mateja Klun   +2 more
doaj   +1 more source

The Role of Hemodynamics through the Circle of Willis in the Development of Intracranial Aneurysm: A Systematic Review of Numerical Models. [PDF]

J Pers Med, 2022
Shen Y, Molenberg R, Bokkers RPH, Wei Y, Uyttenboogaart M, van Dijk JMC.   +5 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source