Results 151 to 160 of about 662,340 (308)
How to Solve Dynamic Stochastic Models Computing Expectations Just Once [PDF]
We introduce a technique called "precomputation of integrals" that makes it possible to compute conditional expectations in dynamic stochastic models in the initial stage of the solution procedure.
Lilia Maliar +2 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
3D numerical simulation of Circulating Fluidized Bed: comparison between theoretical results and experimental measurements of hydrodynamic [PDF]
, 2013 This work was realized in the frame of the European GAYA project supported by ADEME. This paper presents a description of the hydrodynamic into a CFB according to experimental measurements of gas pressure and solid mass flux.
Ansart, Renaud +3 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The short-run dynamics of optimal growth models with delays [PDF]
Differential equations with advanced and delayed time arguments may arise in the optimality conditions of simple growth models with delays. Models with investment gestation lags (time-to-build), consumption gestation lags (habit formation) or learning by
Omar Licandro +2 more
core
Numerical simulation of drifting sand [PDF]
, 2000 Two-phase flows are involved in many industrial and natural flow phenomena varying from as specific as the transport of crude oil in pipelines to as general as the dispersion of pollutants in the atmosphere.
Alhajraf, Salem
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Numerical modelling of vertical drains with advanced constitutive models
, 2006 6th European Conference on Numerical Methods in Geotechnical Engineering - Numerical Methods in Geotechnical Engineering --6 September 2006 through 8 September 2006 -- Graz --When modelling vertical drains in a real boundary value problem the radial flow
Krenn H., Yildiz A., Karstunen M.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Special volume on Advanced Mathematical and Numerical Models in Applied Sciences (AMNMAS)
This Special Issue of Applied Numerical Mathematics contains selected and refereed papers presented at the 21st IMACS World Congress which was held during September 11–15, 2023 in Rome ...
Filipuk, Galina +4 more
core +1 more source