FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Regulating transmission in a spatial oligopoly: a numerical illustration for Belgium [PDF]
This paper introduces strategic behavior of the electricity network operator in a congested network with imperfect competition for generation. It models a two stage Stackelberg game.
Guido Pepermans, Bert Willems
core
SISTEMAS DE SOPORTE DE DECISIONES PARA LA CREACIÓN DE MODELOS NUMÉRICOS HIDRODINÁMICOS
Revista EIAEste artículo hace una corta descripción de las fases y pasos durante el desarrollo de un modelo numérico hidrodinámico y de las características que debe tener un Sistema de Soporte de Decisiones (SSD) que asista al investigador en esta actividad. El SSD
Fernando Toro
doaj
A comprehensive analysis of advanced solar panel productivity and efficiency through numerical models and emotional neural networks. [PDF]
Sci RepBasem A +4 more
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2005 Circulatory models are relevant to research, education and prosthetic devices/components testing. Their structure can be both numerical and physical, according to the specific needs.
Darowski M +5 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A Review of Numerical Models of Radiation Injury and Repair Considering Subcellular Targets and the Extracellular Microenvironment. [PDF]
Int J Mol SciAfshari N +7 more
europepmc +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
An Extensive Study of the Influence of Key Flow Variables on Printed Line Quality Outcomes during Aerosol Jet Printing Using Coupled Three-Dimensional Numerical Models. [PDF]
Materials (Basel)Zhang H +6 more
europepmc +1 more source