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Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source
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Numerical optimization with neuroevolution

Proceedings of the 2002 Congress on Evolutionary Computation. CEC'02 (Cat. No.02TH8600), 2003
Neuroevolution techniques have been successful in many sequential decision tasks, such as robot control and game playing. This paper aims at establishing whether they can be useful in numerical optimization more generally, by comparing neuroevolution to linear programming in a manufacturing optimization domain.
Brian Greer   +3 more
openaire   +1 more source

Positive Bases in Numerical Optimization

Computational Optimization and Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ian D. Coope, Christopher John Price
openaire   +3 more sources

Numerical Verification of Optimality Conditions

SIAM Journal on Control and Optimization, 2008
A class of optimal control problems for a semilinear elliptic partial differential equation with control constraints is considered. It is well known that sufficient second-order conditions ensure the stability of optimal solutions, and the convergence of numerical methods.
Arnd Rösch, Daniel Wachsmuth
openaire   +1 more source

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