Results 251 to 260 of about 245,507 (312)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

Trajectories of Physical Function in Canadian Children With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham   +81 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source
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Numerical optimization with neuroevolution

Proceedings of the 2002 Congress on Evolutionary Computation. CEC'02 (Cat. No.02TH8600), 2003
Neuroevolution techniques have been successful in many sequential decision tasks, such as robot control and game playing. This paper aims at establishing whether they can be useful in numerical optimization more generally, by comparing neuroevolution to linear programming in a manufacturing optimization domain.
Brian Greer   +3 more
openaire   +1 more source

Positive Bases in Numerical Optimization

Computational Optimization and Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ian D. Coope, Christopher John Price
openaire   +2 more sources

Wing design by numerical optimization

Aircraft Systems and Technology Meeting, 1977
A study was conducted to assess the feasibility of performing computerized wing design by numerical optimization. The design program combined a full potential, inviscid aerodynamics code with a conjugate gradient optimization algorithm. Three design problems were selected to demonstrate the design technique.
Raymond M. Hicks, Preston A. Henne
openaire   +1 more source

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